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Unsurprisingly, specified such widespread availability of so inherently attractive a drug, substantial abuse of amphetamine speedily developed. One particular noteworthy 1947 publication hinted at its dimensions. Psychiatrists Russell Monroe and Hyman Drell, stationed at a navy prison in 1945, encountered huge quantities of agitated, hallucinating

The Birch reduction, also referred to as the "Nazi method", became well known in the mid-to-late 1990s and comprised the majority of methamphetamine generation in Michigan in 2002.[106] It reacts pseudoephedrine with liquid anhydrous ammonia and an alkali steel for instance sodium or lithium. The response is allowed to stand until finally the ammon